Transferrin Receptor anticorps

N° du produit ABIN120509

L’anticorps Souris Monoclonal anti-Transferrin Receptor a été validé pour FACS, WB, IP, IHC (fro) et IEM. Il convient pour détecter Transferrin Receptor dans des échantillons de Rat.

Aperçu rapide pour Transferrin Receptor anticorps (ABIN120509)

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin Receptor est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoelectron Microscopy (IEM)

Clone: OX-26

Détail du produit anti-Transferrin Receptor anticorps

Purification: Affinity Chromatography on Protein G.

Immunogène: PHA activated rat lymphocytes. Spleen cells from immunised Balb/c mice were fused with cells from the NS1 mouse myeloma cell line.

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry: Use 10 μL of 1/50-1/200 diluted antibody to label 10^6 cells in 100 μL. Western Blot: This antibody detects a band of approximately 95 kDa in ConA cell lysates under Reducing conditions (MWT 195 kDA without reduction). Immunohistochemistry on Frozen Sections. Immunoprecipitation. Clone MRC OX-26 is reported as suitable for use in Electron Microscopy.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: CD71 / TFRC

Sujet: CD71 is a homodimeric type II transmembrane protein, expressed by all proliferating cells and cells with a requirement for iron, including reticulocytes and capillary endothelium in brain. Transferrin receptor (CD71), transferrin and ferritin have been identified as specialised proteins which control the uptake, transport and storage of free iron in tissues, thereby maintaining iron homeostasis. An imbalance in iron homeostasis within the brain has been linked with the neurodegenerative diseases, Alzheimers, Parkinsons, Huntingtons and Multiple Sclerosis.Synonyms: TfR1, Transferrin receptor protein 1, p90

ID gène: 10116

UniProt: Q99376

Pathways: Transition Metal Ion Homeostasis