CD34 anticorps (FITC)

N° du produit ABIN120582

Détail du produit anti-CD34 anticorps (FITC)

Antigène: CD34

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD34 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Specificité: The antibody reacts with Class III epitope on CD34 (Mucosialin), a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells, it is gradually lost on progenitor cells. The antibody completely blocks binding of Class II antibody QBEnd10 and Class III antibodies BIRMA K3 and 8G12 on KG1a cell line.

Immunogène: Permanent human cell line derived from peripheral leucocytes of a patient suffering from chronic myeloid leukaemia

Clone: 4H11

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL sample. Note: This conjugate is routinely tested on permanent CML cell line MOLM-7.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 15 mM Sodium Azide as preservative and 0.2 % (w/v) high-grade protease free BSA as a stabilizing agent.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détails sur CD34

Antigène: CD34

Autre désignation: CD34 (CD34 Produits)

Synonymes: anticorps AU040960, anticorps CD34 molecule, anticorps CD34 antigen, anticorps CD34, anticorps Cd34

Sujet: CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.Synonyms: Hematopoietic progenitor cell antigen CD34, Hematopoietic progenitor cell marker

ID gène: 947

UniProt: P28906