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CD33 anticorps

CD33 Reactivité: Humain FACS Hôte: Souris Monoclonal HIM3-4 unconjugated
N° du produit ABIN120672
  • Antigène Voir toutes CD33 Anticorps
    CD33
    Reactivité
    • 165
    • 34
    • 14
    • 13
    • 7
    • 6
    • 3
    • 1
    Humain
    Hôte
    • 91
    • 79
    Souris
    Clonalité
    • 88
    • 81
    • 1
    Monoclonal
    Conjugué
    • 56
    • 16
    • 13
    • 12
    • 10
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD33 est non-conjugé
    Application
    • 106
    • 98
    • 40
    • 30
    • 26
    • 26
    • 22
    • 22
    • 16
    • 13
    • 9
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The antibody HIM3-4 reacts with CD33, a 67 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells, it is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
    Purification
    Protein-G affinity chromatography
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    NFMY-9s human cell line
    Clone
    HIM3-4
    Isotype
    IgG1
    Top Product
    Discover our top product CD33 Anticorps primaire
  • Indications d'application
    Flow Cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH ~7.4, 15 mM Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.
    Date de péremption
    12 months
  • Antigène
    CD33
    Autre désignation
    CD33 / SIGLEC3 (CD33 Produits)
    Synonymes
    anticorps SIGLEC-3, anticorps SIGLEC3, anticorps p67, anticorps Siglec-3, anticorps gp67, anticorps CD33 molecule, anticorps CD33 antigen, anticorps CD33, anticorps Cd33
    Sujet
    CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia.Synonyms: Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, Siglec-3, gp67
    ID gène
    945
    UniProt
    P20138
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