CD33 anticorps (AA 261-364)

N° du produit ABIN676958

Il existe 2+ publications pour ce produit. L’anticorps anti-CD33 Polyclonal Lapin est utilisé pour la détection de CD33 dans des échantillons de Humain. Il a été validé pour FACS, WB, IHC (fro), IF (p), IF (cc) et IHC (p).

Aperçu rapide pour CD33 anticorps (AA 261-364) (ABIN676958)

Antigène: CD33

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD33 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CD33 anticorps

Épitope: AA 261-364

Fonction: CD33 Polyclonal Antibody

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CD33

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000),

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CD33 (ABIN676958)

Shi, Jiang, Li, Shan, Li, An, Yang, Xu: "Sodium selenite alters microtubule assembly and induces apoptosis in vitro and in vivo." dans: Journal of hematology & oncology, Vol. 6, Issue 1, pp. 7, (2013) (PubMed).

An, Shi, Wei, Hua, Ci, Jiang, Li, Wu, Hui, Yang, Xu: "The ROS/JNK/ATF2 pathway mediates selenite-induced leukemia NB4 cell cycle arrest and apoptosis in vitro and in vivo." dans: Cell death & disease, Vol. 4, pp. e973, (2013) (PubMed).

Détails sur CD33

Antigène: CD33

Autre désignation: CD33

Sujet:

Synonyms: p67, SIGLEC3, SIGLEC-3, Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, gp67, CD33

Background: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

ID gène: 945

UniProt: P20138