TLR7 anticorps (AA 451-500)

N° du produit ABIN121174

Détail du produit anti-TLR7 anticorps

Antigène: TLR7 (Toll-Like Receptor 7 (TLR7))

Épitope: AA 451-500

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLR7 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: The antibody recognizes human TLR7. Other species not tested.

Purification: Protein-G affinity chromatography

Immunogène: Recombinant human TLR7 (451-500 aa) purified from E. coli

Clone: 4F4

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Western blot (1:500 - 1:2,000), recommended starting dilution is 1:1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détails sur TLR7

Antigène: TLR7 (Toll-Like Receptor 7 (TLR7))

Autre désignation: TLR7 (TLR7 Produits)

Synonymes: anticorps TLR7-like, anticorps RGD1563357, anticorps toll like receptor 7, anticorps toll-like receptor 7, anticorps TLR7, anticorps Tlr7

Sujet: TLR7 is one of toll-like receptors which are type I transmembrane proteins involved in innate immunity by recognizing microbial conserved structures. These proteins are characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain, and act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Human TLR7(hTLR7) is predominantly expressed in lung, placenta and spleen and hTLR7,8 genes are located on the sex chromosome X. hTLR7 may play an important role in detecting and combating viral infections.Synonyms: Toll-like receptor 7

ID gène: 51284

UniProt: Q9NYK1

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades