Endonuclease G anticorps (AA 55-70)

N° du produit ABIN121687

Cet anticorps Lapin Polyclonal détecte spécifiquement Endonuclease G dans WB et IHC (p). Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour Endonuclease G anticorps (AA 55-70) (ABIN121687)

Antigène: Endonuclease G (ENDOG)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Endonuclease G est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Endonuclease G anticorps

Épitope: AA 55-70

Purification: Affinity chromatography

Immunogène: Synthetic peptide corresponding to amino acids 55 - 70 of endonuclease G. AA Sequence: GGPRGPGELAKYGLP

Information d'application

Indications d'application: Western Blot: 1 μg/mL - 2 μg/mL, this antibody detects a band of approximately 35 kDa in HepG2 and 3T3 cell lysates. Immunohistochemistry on paraffin sections: 15 μg/mL, Sodium citrate buffer pH 6.0 is recommended for this purpose. Recommended Positive Control: Human pancreas.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détails sur Endonuclease G

Antigène: Endonuclease G (ENDOG)

Autre désignation: Endonuclease G

Sujet: Endonuclease G is a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis. endoG is reported to act independently of caspases and may represent a caspase independent apoptotic pathway initiated from the mitochondria.Synonyms: ENDOG

UniProt: Q14249

Pathways: Apoptose