CXCR5 anticorps (Cytoplasmic Domain)

N° du produit ABIN121946

L’anticorps anti-CXCR5 Polyclonal Lapin est utilisé pour la détection de CXCR5 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour CXCR5 anticorps (Cytoplasmic Domain) (ABIN121946)

Antigène: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR5 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CXCR5 anticorps

Épitope: Cytoplasmic Domain

Specificité: Recognizes Human CXC Chemokine Receptor 5 (CXCR5) (family: GPCR, subfamily: Chemokine). BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except MTA3 (50 %).

Réactivité croisée (Details): Species reactivity (expected):Hamster, Mouse, Pig, Rabbit, Rat.
Species reactivity (tested):Human, Gibbon, Gorilla.

Purification: Peptide Immunoaffinity Chromatography

Immunogène: Synthetic peptide - KLH conjugated.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry with formalin fixed paraffin embedded tissues: 5-18 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-80 °C

Stockage commentaire: Store the antibody at 2-8 °C for up to one month or at -70 °C for longer. Avoid repeatedfreezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CXCR5

Antigène: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Autre désignation: CD185 / CXCR5

Sujet: CXCR5, a Chemokine Receptor, is required for normal development of Peyer's patches, inguinal lymph nodes, and splenic follicles. CXCR5 binds B-lymphocyte chemoattractant (BLC) and is involved in B-cell homing to follicles in lymph nodes and spleen. Two isoforms are produced by alternative splicing. CXCR5 expression has been reported in human blood and salivary gland and in animal lymphatic organs, blood, bone marrow, brain, liver, lymph node, skin, spleen, stomach, and tonsil. ESTs have been isolated from human brain, germ cell, lung, lymph, pancreas, skin, stomach, and uterus cancer libraries, and from normal human blood, liver/spleen, lymph node, nerve, placenta, small intestine, tonsil, and B-cell/lung/testis libraries.Synonyms: BLR1, Burkitt lymphoma receptor 1, C-X-C chemokine receptor type 5, CXC-R5, CXCR-5, MDR15, Monocyte-derived receptor 15

ID gène: 643

UniProt: P32302