CCR1 anticorps (Extracellular Domain)

N° du produit ABIN121947

Cet anticorps anti-CCR1 est un anticorps Lapin Polyclonal détectant CCR1 dans IHC (p). Adapté pour Humain et Souris.

Aperçu rapide pour CCR1 anticorps (Extracellular Domain) (ABIN121947)

Antigène: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CCR1 anticorps

Épitope: Extracellular Domain

Specificité: Reacts with human C-C Chemokine Receptor 1 (CCR1, Family: GPCR, subfamily: Chemokine).

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic petide - KLH conjugated.

Information d'application

Indications d'application: Immunohistochemistry on paraffin embedded sections: 5 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CCR1

Antigène: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Autre désignation: CD191 / CCR1

Sujet: CCR1, a Chemokine Receptor, affects stem cell proliferation and mediates systemic inflammatory responses. This receptor is stimulated by the beta chemokines RANTES, MCP-1, and MIP-1 alpha. Disruption of CCR1 enhances protection from pulmonary inflammation and reduces the development of respiratory distress syndrome in rat. CCR1 is widely expressed, particularly in hematopoietic cells from blood, vessels, and bone marrow. This receptor has also been reported to be expressed in lung, brain, placenta, heart, skeletal muscle, and kidney. ESTs have been isolated from blood, kidney, liver/spleen, lung, placenta, uterus, and vessel libraries.Synonyms: C-C CKR-1, C-C chemokine receptor type 1, CC-CKR-1, CCR-1, CMKBR1, CMKR1, HM145, LD78 receptor, MIP1 alpha Receptor, Macrophage inflammatory protein 1-alpha receptor, RANTES-R, SCYAR1

ID gène: 1230

UniProt: P32246