DRD4 anticorps (C-Term)
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- Antigène Voir toutes DRD4 Anticorps
- DRD4 (Dopamine Receptor D4 (DRD4))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DRD4 est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- Detects Dopamine Receptor D4 (family: GPCR, subfamily: Dopamine)
- Purification
- Peptide immunogen affinity column
- Immunogène
- Synthetic peptide - KLH conjugated
- Top Product
- Discover our top product DRD4 Anticorps primaire
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- Indications d'application
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Immunohistochemistry on paraffin embedded sections: 10 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. - Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- PBS, pH 7.7, containing 0.01 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-80 °C
- Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Date de péremption
- 12 months
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- Antigène
- DRD4 (Dopamine Receptor D4 (DRD4))
- Autre désignation
- Dopamine D4 Receptor (DRD4 Produits)
- Synonymes
- anticorps Drd4b, anticorps si:ch211-69h5.1, anticorps zgc:123021, anticorps D4DR, anticorps AW125663, anticorps D4R, anticorps Drd-4, anticorps D4RA, anticorps DRD4, anticorps Drd4c, anticorps dopamine receptor D4 related sequence, anticorps dopamine receptor D4, anticorps dopamine receptor D4b, anticorps drd4-rs, anticorps DRD4, anticorps Drd4, anticorps SRU_2808, anticorps MSMEG_3522, anticorps drd4b
- Sujet
- Dopamine Receptor D4 (DRD4), a Dopamine Receptor, has been suggested to affect personality, substance dependence, cognition, and emotion. DRD4 binds the antipsychotic medications clozapine and spiperone. DRD4 knock-out mice are anatomically normal but display altered locomotion and sensitivity to drugs such as clozapine, cocaine, and others. The DRD4 gene contains extensive polymorphisms consisting of variable numbers of tandem repeats (VNTR) in sequences corresponding to the third cytoplasmic loop of the receptor, at least 27 different haplotypes encoding 20 different protein variants have been documented. The frequency of the different variants varies among population groups. Studies have suggested a link between VNTR and human personality traits (such as novelty seeking) and diseases (such as schizophrenia, bipolar affective disorder, and Tourette syndrome), however, considerable debates exist regarding the validity and significance of such associations. DRD4 expression has been reported in various regions of the brain as well as in adrenal gland, artery, eye, heart, kidney, placenta, spinal cord, testis, and vas deferens. ESTs have been isolated from a kidney library.Synonyms: D(2C) dopamine receptor, D(4) dopamine receptor, DRD4
- ID gène
- 1815
- UniProt
- P21917
- Pathways
- cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity
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