Lipoprotein Lipase anticorps

N° du produit ABIN125994

Cet anticorps anti-Lipoprotein Lipase est un anticorps Souris Monoclonal détectant Lipoprotein Lipase dans WB, IHC (fro), Func et EIA. Adapté pour Humain et Boeuf (Vache).

Aperçu rapide pour Lipoprotein Lipase anticorps (ABIN125994)

Antigène: Lipoprotein Lipase (LPL)

Reactivité: Humain, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Lipoprotein Lipase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Enzyme Immunoassay (EIA)

Clone: Mab-7

Détail du produit anti-Lipoprotein Lipase anticorps

Specificité: This Monoclonal antibody is directed against the CII binding site. Blocks the catalytic activity of Bovine milk lipase. A small partial cross-reactivity with Human Heparin Plasma Lipase activity was observed (Ref. 1).

Réactivité croisée (Details): Species reactivity (tested):Bovine, weak cross-reactivity with Human.

Purification: Affinity Chromatography on Protein A

Immunogène: Purified Bovine Lipoprotein Lipase

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Immunoblotting. Immunohistochemistry (1/10). Dilution buffer: PBS with 0.5 % BSA and 0.1 % Na-Azide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1 mL distilled water

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Lipoprotein Lipase

Antigène: Lipoprotein Lipase (LPL)

Autre désignation: Lipoprotein Lipase

Sujet: Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation.Synonyms: EC=3.1.1.34, LIPD, LPL

ID gène: 4023

NCBI Accession: NP_000228

UniProt: P06858

Pathways: Lipid Metabolism