LYVE1 anticorps (AA 24-232) (Biotin)

N° du produit ABIN126136

Cet anticorps Lapin Polyclonal détecte spécifiquement LYVE1 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour LYVE1 anticorps (AA 24-232) (Biotin) (ABIN126136)

Antigène: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LYVE1 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Détail du produit anti-LYVE1 anticorps (Biotin)

Épitope: AA 24-232

Specificité: The antibody recognizes LYVE-1.

Purification: Antigen Affinity Chromatography.

Immunogène: Recombinant Human soluble LYVE-1 (24-232) produced in insect cells. Remarks: The recombinant soluble LYVE-1 consists of amino acid 24 (Ser) to 232 (Gly) and is fused to a C-terminal His-tag (6xHis).

Information d'application

Indications d'application: The unconjugated antibody can be used for ELISA experiments, Western blotting, FACSand Cell Sorting (Use at 2-5 μg/mL together with the appropriate secondary reagents).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with sterile water to a concentration of 50 μg/mL

Buffer: 0.1 M Tris-Cl, 0.1 M NaCl, pH 7.4 containing 0.02 % Sodium Azide as preservative and 50x BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur LYVE1

Antigène: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Autre désignation: LYVE-1

Sujet: LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41 % similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 Molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 Molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.Synonyms: CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, LYVE1, Lymphatic vessel endothelial hyaluronic acid receptor 1, XLKD1

ID gène: 10894

NCBI Accession: NP_006682

UniProt: Q9Y5Y7

Pathways: Glycosaminoglycan Metabolic Process