CD22 anticorps (pTyr1150, pTyr1151)

N° du produit ABIN126818

L’anticorps Souris Monoclonal anti-CD22 a été validé pour WB et EIA. Il convient pour détecter CD22 dans des échantillons de Humain.

Aperçu rapide pour CD22 anticorps (pTyr1150, pTyr1151) (ABIN126818)

Antigène: CD22 (CD22 Molecule (CD22))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD22 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 10C3

Détail du produit anti-CD22 anticorps

Épitope: pTyr1150, pTyr1151

Specificité: This antibody recognizes Insulin receptor phosphorylated at tyrosine residues 1150/1151 and also the IGF1 receptor.

Attributs du produit: Synonyms: IR, INSR, IGF-I receptor, IGFR, IGF1R

Purification: Size exclusion chromatography

Ingrédients: incl. positive Control

Immunogène: Synthetic phosphopeptide conjugated to KLH.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. Positive Control: Cell lysate from insulin-treated HEK-293 cells. ELISA: 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS/0.09 Na-Azide/PEG and Sucrose/50 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD22

Antigène: CD22 (CD22 Molecule (CD22))

Autre désignation: CD22

Sujet: The insulin receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. The insulin receptor is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional phosphorylation sites such as tyrosine residues 960, 1316, and 1322 regulate the assembly of signal transduction complexes.Synonyms: B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM, Leu-14, SIGLEC2, Sialic acid-binding Ig-like lectin 2, Siglec-2