LEF1 anticorps
Aperçu rapide pour LEF1 anticorps (ABIN126828)
Antigène
Voir toutes LEF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody specifically recognizes LEF at 55-57 kDa. It does not crossreact with TCF3 and TCF4.
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Attributs du produit
- Synonyms: Lymphoid enhancer-binding factor 1, LEF-1, T cell-specific transcription factor 1-alpha,TCF1-alpha
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Purification
- Size exclusion chromatography
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Immunogène
- Recombinant LEF
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Isotype
- IgG1
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Indications d'application
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Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. ELISA: 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.1mg/mL
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Buffer
- PBS/0.09 % Na-Azide/PEG and Sucrose/50 % Glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
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Autre désignation
- LEF1
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Sujet
- LEF is a transcription factor of the LEF/TCF protein family. LEF interacts with cytoplasmic beta-catenin and regulates the expression of genes containing a LEF/TCF binding site. The formation of LEF - beta-catenin heterodimers is an important step in the wnt/wg signal transduction pathway.Synonyms: LEF-1, Lymphoid enhancer-binding factor 1, T cell-specific transcription factor 1-alpha, TCF1-alpha
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ID gène
- 51176
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UniProt
- Q9UJU2
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Pathways
- Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
Antigène
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