CD40 Ligand anticorps

N° du produit ABIN127037

L’anticorps anti-CD40 Ligand Polyclonal Lapin est utilisé pour la détection de CD40 Ligand dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour CD40 Ligand anticorps (ABIN127037)

Antigène: CD40 Ligand (CD40LG)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD40 Ligand est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD40 Ligand anticorps

Specificité: This antibody detects CD40L.

Purification: Affinity chromatography

Immunogène: Synthetic peptide surrounding amino acid 246 of human CD40 Ligand

Information d'application

Indications d'application: Western blot (0.5-4 μg/mL). Recommended positive control: Jurkat cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid Repeated freeze/defrost cycles.

Stock: -20 °C

Stockage commentaire: Store (in aliquots) at -20 °C.

Détails sur CD40 Ligand

Antigène: CD40 Ligand (CD40LG)

Autre désignation: CD154 / CD40L

Sujet: CD40 is a type I membrane protein found on the surface of B cells and primary carcinomas. It belongs to the TNF-R family. CD40 serves as the receptor for CD40 ligand (CD40L), a cytokine expressed on the cell surface of T cells. CD40 plays a critical role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with T cells expressing CD40L, and activation of CD4+ T cells. Ligation of CD40 with its ligand preferentially induces stress-activated protein kinases in B lymphocytes.Synonyms: CD40 ligand, CD40-L, CD40LG, GP39, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TRAP, Tumor necrosis factor ligand superfamily member 5

ID gène: 959

NCBI Accession: NP_000065

UniProt: P29965

Pathways: Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints