Caspase 6 anticorps (C-Term)

N° du produit ABIN127060

Cet anticorps Lapin Polyclonal détecte spécifiquement Caspase 6 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Caspase 6 anticorps (C-Term) (ABIN127060)

Antigène: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Caspase 6 anticorps

Épitope: C-Term

Specificité: The antibody detects a full length (35 kDa) and the cleaved fragment (18 kDa) of Caspase-6.

Purification: Affinity Purified

Immunogène: Synthetic peptide mapping to the C-terminus of Rat Caspase-6 large fragment.

Information d'application

Indications d'application: Western Blot: 0.5-4 μg/mL. Jurkat cell lysate, mouse intestine, and rat kidney tissue lysate can be used as a positivecontrols.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.2 containing 30 % Glycero, 0.01 Thimerosal, 0.5 % BSA

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur Caspase 6

Antigène: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Autre désignation: Caspase-6

Sujet: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-6 is one of the major executioner caspases functioning in cellular apoptotic processes. Similar as other caspases, caspase-6 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Together with caspase-3, caspase-6 is one of the major caspases in apoptotic cells, and functions downstream of apoptosis inhibitors Bcl-2 and Bcl-xL. Caspase-6 has also been shown involving in the proteolysis of poly (ADP-ribose) polymerase (PARP) and nuclear lamin A.Synonyms: Apoptotic protease Mch-2, CASP-6, CASP6, MCH-2, MCH2

ID gène: 839

NCBI Accession: NP_001217

UniProt: P55212

Pathways: Apoptose, Caspase Cascade in Apoptosis