RGS3 anticorps (AA 401-519)

N° du produit ABIN127074

Cet anticorps anti-RGS3 est un anticorps Lapin Polyclonal détectant RGS3 dans WB et IP. Adapté pour Humain.

Aperçu rapide pour RGS3 anticorps (AA 401-519) (ABIN127074)

Antigène: RGS3 (Regulator of G-Protein Signaling 3 (RGS3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS3 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-RGS3 anticorps

Épitope: AA 401-519

Specificité: This antibody detects human RGS3. Other species not tested.

Purification: Protein A chromatography

Immunogène: E. coli-expressed human RGS3 (aa 401-519)

Information d'application

Indications d'application: Western Blot: 1.0 μg/mL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.

Détails sur RGS3

Antigène: RGS3 (Regulator of G-Protein Signaling 3 (RGS3))

Autre désignation: RGS3

Sujet: RGS3 (regulator of G protein signaling 3) is a 519-residue protein that is widely expressed in many tissues and cells. The protein contains an RGS domain near the carboxy terminus that serves as a GTPase-activating protein (GAP). RGS3 negatively regulates the activation of Giα and Gαq. A truncated RGS3 (RGS3T), with its N-terminal 313 residues removed, has been shown to negatively regulate acenylyl cyclase and PLC. RGS3T may be localized in the nucleus and RGS3 is found in cytoplasm. Translocation to membrane is important for the RGS proteins to interact with heterotrimeric G proteins.Synonyms: RGP3, Regulator of G-protein signaling 3

ID gène: 5998

NCBI Accession: NP_060260

UniProt: P49796

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling