CCR1 anticorps
Aperçu rapide pour CCR1 anticorps (ABIN127096)
Antigène
Voir toutes CCR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- The anti-CCR1 antibody recognizes 42 kDa CCR1 in Western blot analysis.
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Purification
- Protein G purified
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Immunogène
- Recombinant human CCR1
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Indications d'application
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Western Blot: 1-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C/-80 °C
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Stockage commentaire
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))
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Autre désignation
- CD191 / CCR1
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Sujet
- Chemokines play an important role in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation.Synonyms: C-C CKR-1, C-C chemokine receptor type 1, CC-CKR-1, CCR-1, CMKBR1, CMKR1, HM145, LD78 receptor, MIP1 alpha Receptor, Macrophage inflammatory protein 1-alpha receptor, RANTES-R, SCYAR1
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ID gène
- 1230
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NCBI Accession
- NP_001286
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UniProt
- P32246
Antigène
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