TLR1 anticorps

N° du produit ABIN127125

Cet anticorps anti-TLR1 est un anticorps Chèvre Polyclonal détectant TLR1 dans WB et EIA. Adapté pour Humain.

Aperçu rapide pour TLR1 anticorps (ABIN127125)

Antigène: TLR1 (Toll-Like Receptor 1 (TLR1))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-TLR1 anticorps

Purification: Antigen affinity chromatography

Immunogène: Recombinant human TLR1

Information d'application

Indications d'application: Western Blot: 1: 200 - 1: 1000. ELISA: 1: 100 - 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.

Détails sur TLR1

Antigène: TLR1 (Toll-Like Receptor 1 (TLR1))

Autre désignation: CD281 / TLR1

Sujet: The TLR (toll-like receptors) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFκB and suggests that these receptors are involved in mediating inflammatory responses. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes. TLR6 is highly homologous to TLR1, sharing greater that 65 % sequence identity, and, like other members of TLR family, it induces NFκB signaling upon activation.Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein

ID gène: 9606

UniProt: Q15399

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades