FKBP1A anticorps

N° du produit ABIN127265

L’anticorps anti-FKBP1A Polyclonal Lapin est utilisé pour la détection de FKBP1A dans des échantillons de Humain, Souris, Rat, Boeuf (Vache) et Lapin. Il a été validé pour WB, IP et IHC (p).

Aperçu rapide pour FKBP1A anticorps (ABIN127265)

Antigène: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP1A est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-FKBP1A anticorps

Specificité: The antibody detects 12 kDa FKBP12 protein.

Purification: Affinity purified

Immunogène: Synthetic peptide surrounding amino acid 10 of human FKBP1A/FKBP12.

Information d'application

Indications d'application: Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 2-10 μg/mL. Immunohistochemistry: 2-10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur FKBP1A

Antigène: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Autre désignation: FKBP1A / FKBP12

Sujet: FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway.Synonyms: FK506-binding protein 1A, Immunophilin FKBP12, PPIase FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, Rotamase

ID gène: 2280

NCBI Accession: NP_000792

UniProt: P62942

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process