Annexin VIII anticorps
Aperçu rapide pour Annexin VIII anticorps (ABIN127268)
Antigène
Voir toutes Annexin VIII (ANXA8) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- The antibody detects 36 kDa annexin VIII of Human origin. The ~28-30 kDa cleavage fragments can also be detected in Jurkat cell lysate. Blocking peptide is available separately (AP00292CP-N).
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Purification
- Protein A Affinity Chromatography
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Immunogène
- Synthetic peptide surrounding amino acid 316 of Human Annexin VIII.
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Indications d'application
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Western Blot: 0.5-4 μg/mL, Jurkat cell lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS, pH 7.2 containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C/-80 °C
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Stockage commentaire
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- Annexin VIII (ANXA8) (Annexin A8 (ANXA8))
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Autre désignation
- Annexin A8 / ANXA8
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Sujet
- The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain which binds to phospholipids in a Ca2+-dependent manner. Annexin family members have been implicated as regulators of diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. Annexin VIII is preferentially expressed in acute promyelocytic leukemia (APL) cells which may relate its role in hematopoietic cell differentiation.Synonyms: ANX8, Annexin VIII, Annexin-8, VAC-beta, Vascular anticoagulant-beta
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ID gène
- 244
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NCBI Accession
- NP_001035173
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UniProt
- P13928
Antigène
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