BIN1 anticorps

N° du produit ABIN127306

Cet anticorps Lapin Polyclonal détecte spécifiquement BIN1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BIN1 anticorps (ABIN127306)

Antigène: BIN1 (Bridging Integrator 1 (BIN1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIN1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BIN1 anticorps

Specificité: The antibody recognizes ~65 kDa band of BIN-1. A cleavage fragment (~45 kDa) can also be detected in apoptotic samples.

Purification: Immunoaffinity

Immunogène: Synthetic peptide corresponding to residues surrounding amino acids 578 of mouse BIN-1

Information d'application

Indications d'application: Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS containing 0.1 % BSA, 30 % glycerol, and 0.01 % thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur BIN1

Antigène: BIN1 (Bridging Integrator 1 (BIN1))

Autre désignation: BIN1 / AMPHL

Sujet: BIN-1 is a tumor suppressor protein that was identified in a genetic screen for proteins that interact with the MCY oncoprotein. BIN-1 inhibits the oncogenic activity of MYC, possibly through activating or facilitating apoptosis. BIN is a short-lived protein with a half-life of about 2 hours.Synonyms: Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, Myc box-dependent-interacting protein 1

ID gène: 274

NCBI Accession: NP_004296

UniProt: O00499