DCLRE1C anticorps (Internal Region)
Aperçu rapide pour DCLRE1C anticorps (Internal Region) (ABIN129558)
Antigène
Voir toutes DCLRE1C AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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N° du produit (Fournisseur)
- 600-101-293
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Fournisseur
- Rockland
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Fonction
- ARTEMIS Antibody
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Réactivité croisée (Details)
- This antibody detects a band of the appropriate size in a number of different cell lines.
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Attributs du produit
- Synonyms: goat anti-Artemis Antibody, A-SCID antibody, A SCID protein antibody, protein Artemis antibody, DCLRE1C antibody, DCLRE1C, DNA cross link repair 1C antibody, ASCID, SCIDA, SNM1C
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Purification
- This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.
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Stérilité
- Sterile filtered
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Immunogène
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Immunogen: This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding an internal region of Human ARTEMIS (DCLRE1C DNA cross-link repair 1C).
Immunogen Type: Conjugated Peptide
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Isotype
- IgG
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Indications d'application
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Immunohistochemistry Dilution: 1:1,000
Application Note: This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and western blotting. Reactivity in other immunoassays is unknown. This antibody detects a band of approximately 90 kDa (predicted molecular weight: 78 kDa).
Western Blot Dilution: 1:500 - 1:2,000
ELISA Dilution: 1:10,000 - 1:20,000
Other: User Optimized
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.2 mg/mL
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Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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Date de péremption
- 12 months
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- DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
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Autre désignation
- DCLRE1C
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Sujet
- Background: Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNA-PKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.
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ID gène
- 64421, 76496495
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UniProt
- Q96SD1
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Pathways
- Réparation de l'ADN
Antigène
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