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DCLRE1C anticorps (Internal Region)

Cet anticorps anti-DCLRE1C est un anticorps Chèvre Polyclonal détectant DCLRE1C dans WB, ELISA et IHC. Adapté pour Humain.
Rockland
N° du produit ABIN129558
N° du produit (Fournisseur): 600-101-293

Aperçu rapide pour DCLRE1C anticorps (Internal Region) (ABIN129558)

Antigène

Voir toutes DCLRE1C Anticorps
DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Reactivité

  • 41
  • 28
  • 25
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 55
  • 2
Chèvre

Clonalité

  • 57
Polyclonal

Conjugué

  • 31
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp DCLRE1C est non-conjugé

Application

  • 43
  • 24
  • 20
  • 13
  • 13
  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Épitope

    • 15
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    N° du produit (Fournisseur)

    600-101-293

    Fournisseur

    Rockland

    Fonction

    ARTEMIS Antibody

    Réactivité croisée (Details)

    This antibody detects a band of the appropriate size in a number of different cell lines.

    Attributs du produit

    Synonyms: goat anti-Artemis Antibody, A-SCID antibody, A SCID protein antibody, protein Artemis antibody, DCLRE1C antibody, DCLRE1C, DNA cross link repair 1C antibody, ASCID, SCIDA, SNM1C

    Purification

    This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.

    Stérilité

    Sterile filtered

    Immunogène

    Immunogen: This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding an internal region of Human ARTEMIS (DCLRE1C DNA cross-link repair 1C).

    Immunogen Type: Conjugated Peptide

    Isotype

    IgG
  • Indications d'application

    Immunohistochemistry Dilution: 1:1,000

    Application Note: This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and western blotting.  Reactivity in other immunoassays is unknown. This antibody detects a band of approximately 90 kDa (predicted molecular weight: 78 kDa).

    Western Blot Dilution: 1:500 - 1:2,000

    ELISA Dilution: 1:10,000 - 1:20,000

    Other: User Optimized

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.2 mg/mL

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Date de péremption

    12 months
  • Antigène

    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

    Autre désignation

    DCLRE1C

    Sujet

    Background: Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNA-PKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.

    ID gène

    64421, 76496495

    UniProt

    Q96SD1

    Pathways

    Réparation de l'ADN
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