POLM anticorps (AA 6-18)

N° du produit ABIN129588

N° du produit (Fournisseur): 600-401-462

Cet anticorps anti-POLM est un anticorps Lapin Polyclonal détectant POLM dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour POLM anticorps (AA 6-18) (ABIN129588)

Antigène: POLM (Polymerase (DNA Directed), mu (POLM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLM est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-POLM anticorps

Épitope: AA 6-18

N° du produit (Fournisseur): 600-401-462

Fournisseur: Rockland

Fonction: POLM Mu Antibody

Attributs du produit: Synonyms: rabbit anti-POLM antibody, DNA-directed DNA/RNA polymerase mu , Pol Mu, Terminal transferase, DNA Polymerase Mu antibody, DNA-directed DNA polymerase mu antibody, Pol iota antibody

Purification: This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.

Stérilité: Sterile filtered

Immunogène:

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to aa 6-18 of Human POLM m (DNA polymerase mu).  POLM mu is a template-directed terminal deoxynucleotide transferase that shows a preferential expression in proliferating lymphoid cells.

Immunogen Type: Conjugated Peptide

Isotype: IgG

Information d'application

Indications d'application:

Application Note: This affinity purified antibody has been tested for use in ELISA against the immunizing peptide.  Reactivity in other immunoassays is unknown.

Western Blot Dilution: 1:500- 1:2,000

ELISA Dilution: 1:10,000 - 1:50,000

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.1 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur POLM

Antigène: POLM (Polymerase (DNA Directed), mu (POLM))

Autre désignation: POLM

Sujet: Background: DNA-directed DNA/RNA polymerase mu (POLM) is a Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). It participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. DPOLM has a reduced ability to distinguish dNTP and rNTP as substrates, and elongates them on DNA primer strand with a similar efficiency. It is able to polymerize nucleotides on RNA primer strands.

ID gène: 27434

UniProt: Q9NP87

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response