USP18 anticorps (AA 25-50)

N° du produit ABIN129593

N° du produit (Fournisseur): 600-401-476

L’anticorps Lapin Polyclonal anti-USP18 a été validé pour WB, ELISA et FM. Il convient pour détecter USP18 dans des échantillons de Humain.

Aperçu rapide pour USP18 anticorps (AA 25-50) (ABIN129593)

Antigène: USP18 (Ubiquitin Specific Peptidase 18 (USP18))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP18 est non-conjugé

Application: Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)

Détail du produit anti-USP18 anticorps

Épitope: AA 25-50

N° du produit (Fournisseur): 600-401-476

Fournisseur: Rockland

Fonction: UBP43 Antibody

Réactivité croisée (Details): This affinity-purified antibody is directed against human UBP43 protein.

Attributs du produit: Synonyms: rabbit anti-UBP43 antibody, rabbit anti-USP18 antibody, rabbit anti-ISG43 antibody, 43 kDa ISG15 specific protease antibody, hUBP43 antibody, Interferon Stimulated Gene 43 kD antibody, ISG15 Specific Processing Protease antibody, ISG43 antibody, Ubiquitin Specific Peptidase 18 antibody, Ubl carboxyl-terminal hydrolase 18, Ubl thioesterase 18

Purification: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Stérilité: Sterile filtered

Immunogène:

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 25-50 of human UBP43 protein.

Immunogen Type: Conjugated Peptide

Isotype: IgG

Information d'application

Indications d'application:

Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 43 kDa in size corresponding to UBP43 by western blotting in the appropriate cell lysate or extract.

Western Blot Dilution: 1:500 - 1:2,000

ELISA Dilution: 1:10,000 - 1:50,000

IF Microscopy Dilution: User Optimized

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.9 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur USP18

Antigène: USP18 (Ubiquitin Specific Peptidase 18 (USP18))

Autre désignation: USP18

Sujet: Background: UBP43 (also known as ISG43, Ubl thiolesterase 18, ISG15-specific processing protease, 43 kDa ISG15-specific protease, ubiquitin specific protease 18 or USP18) is a member of the deubiquitinating protease family of enzymes, which removes ubiquitin adducts from a broad range of protein substrates. Deletion of the UBP43 gene in mouse leads to a massive increase of ISG15 conjugates in tissues indicating that UBP43 is a major ISG15-specific protease. UBP43 is the first ISG15-specific protease reported.  Both ISG15 and UBP43 genes are known to be strongly induced by interferon, genotoxic stress, and viral infection. Thus UBP43 may be necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.

ID gène: 11274, 32313610

UniProt: Q9UMW8