GLI2 anticorps (Internal Region)

N° du produit ABIN129624

Détail du produit anti-GLI2 anticorps

Antigène: GLI2 (GLI Family Zinc Finger 2 (GLI2))

Épitope: Internal Region

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLI2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids from an of Mouse Gli-2.

Isotype: IgG

Information d'application

Indications d'application: This antibody has been tested for use in ELISA, immunohistochemistry and western blot.  Specific conditions for reactivity should be optimized by the end user. See figure legend for expectations by WB and IHC.  Multiple splice variants have been reported for this protein.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.02 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-GLI2 (ABIN129624)

Guntur, Reinhold, Cuellar, Naski: "Conditional ablation of Pten in osteoprogenitors stimulates FGF signaling." dans: Development (Cambridge, England), Vol. 138, Issue 7, pp. 1433-44, (2011) (PubMed).

Détails sur GLI2

Antigène: GLI2 (GLI Family Zinc Finger 2 (GLI2))

Autre désignation: Gli-2 (GLI2 Produits)

Synonymes: anticorps HPE9, anticorps THP1, anticorps THP2, anticorps GLI2/GLI4, anticorps GLI3, anticorps AW546128, anticorps GLI family zinc finger 2, anticorps GLI-Kruppel family member GLI2, anticorps GLI2, anticorps Gli2

Sujet: Gli-2 (also known as Zinc Finger Protein Gli-2, GLI-Kruppel family member GLI-2 or Tax helper protein) belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors that bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling, and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. Gli-2 is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes: Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, pre-axial
Synonyms: Gli 2 antibody, GLI family zinc finger 2 antibody, GLI kruppel family member 2 antibody, GLI Kruppel family member GLI2 antibody, Oncogene GLI2 antibody, Tax helper protein antibody, Tax helper protein 2 antibody

ID gène: 14633, 124487481

UniProt: Q8K0K3

Pathways: Signalisation Hedgehog, Dopaminergic Neurogenesis