PDGFRB anticorps

N° du produit ABIN1302413

L’anticorps Souris Monoclonal anti-PDGFRB a été validé pour ICC et FACS. Il convient pour détecter PDGFRB dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour PDGFRB anticorps (ABIN1302413)

Antigène: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PDGFRB est non-conjugé

Application: Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 18A2

Détail du produit anti-PDGFRB anticorps

Fonction: Anti-Hu CD140b Purified

Specificité: The monoclonal antibody 18A2 recognizes an extracellular epitope of CD140b / PDGF-RB, the 180-190 kDa beta chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative roles.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: CD140b-transfected NIH 3T3 cells

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-PDGFRB (ABIN1302413)

Fekete, Rojewski, Fürst, Kreja, Ignatius, Dausend, Schrezenmeier: "GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC." dans: PLoS ONE, Vol. 7, Issue 8, pp. e43255, (2012) (PubMed).

Détails sur PDGFRB

Antigène: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Autre désignation: CD140b

Sujet: Platelet derived growth factor receptor beta,CD140b / PDGF-RB (platelet-derived growth factor receptor beta) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with CD140a / PDGF-RA. Whereas CD140a can have both pro-proliferative or anti-proliferative effects, the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumours such as medulloblastoma.,PDGFRB, PDGFR1

ID gène: 5159

UniProt: Q59F04

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling