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PDGFRB anticorps

PDGFRB Reactivité: Humain FACS, ICC Hôte: Souris Monoclonal 18A2 unconjugated
N° du produit ABIN1302413
  • Antigène Voir toutes PDGFRB Anticorps
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    Reactivité
    • 219
    • 102
    • 82
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 184
    • 41
    • 6
    • 2
    Souris
    Clonalité
    • 171
    • 62
    Monoclonal
    Conjugué
    • 115
    • 13
    • 10
    • 10
    • 10
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    Cet anticorp PDGFRB est non-conjugé
    Application
    • 162
    • 81
    • 54
    • 54
    • 53
    • 36
    • 33
    • 26
    • 16
    • 13
    • 11
    • 9
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Specificité
    The monoclonal antibody 18A2 recognizes an extracellular epitope of CD140b / PDGF-RB, the 180-190 kDa beta chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative roles.
    Réactivité croisée (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    CD140b-transfected NIH 3T3 cells
    Clone
    18A2
    Isotype
    IgG1
    Top Product
    Discover our top product PDGFRB Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Fekete, Rojewski, Fürst, Kreja, Ignatius, Dausend, Schrezenmeier: "GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC." dans: PLoS ONE, Vol. 7, Issue 8, pp. e43255, (2012) (PubMed).

  • Antigène
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    Abstract
    PDGFRB Produits
    Synonymes
    anticorps AI528809, anticorps CD140b, anticorps PDGFR-1, anticorps Pdgfr, anticorps CD140B, anticorps IBGC4, anticorps JTK12, anticorps PDGFR, anticorps PDGFR1, anticorps platelet derived growth factor receptor, beta polypeptide, anticorps platelet derived growth factor receptor beta, anticorps Pdgfrb, anticorps PDGFRB
    Sujet
    Platelet derived growth factor receptor beta,CD140b / PDGF-RB (platelet-derived growth factor receptor beta) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with CD140a / PDGF-RA. Whereas CD140a can have both pro-proliferative or anti-proliferative effects, the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumours such as medulloblastoma.,PDGFRB, PDGFR1
    ID gène
    5159
    UniProt
    Q59F04
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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