Notch1 anticorps (Extracellular, N-Term)

N° du produit ABIN1304873

L’anticorps Souris Monoclonal anti-Notch1 a été validé pour WB, ELISA et ICC. Il convient pour détecter Notch1 dans des échantillons de Souris.

Aperçu rapide pour Notch1 anticorps (Extracellular, N-Term) (ABIN1304873)

Antigène: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Notch1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: N253-32

Détail du produit anti-Notch1 anticorps

Épitope: AA 20-216, Extracellular, N-Term

Fonction: Anti-Notch1 Antibody

Specificité: No off-targets reported for Notch2 or Notch3

Réactivité croisée: Rat

Attributs du produit: Our Anti-Notch1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N253/32. It detects mouse and rat Notch1, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Pureté: Purified mAbs are >90 % specific antibody.

Immunogène: Fusion protein amino acids 20-216 (extracellular N-terminus, EGF-like domains 1-5) of mouse Notch1 (accession number Q01705) produced recombinantly in E. Coli

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 24 months

Détails sur Notch1

Antigène: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Autre désignation: Notch1

Sujet:

Synonyms: Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT), Notch 1 intracellular domain (NICD)]

Description Logic: Our Anti-Notch1 mouse monoclonal primary antibody is produced from hybridoma clone N253/32. It detects mouse and rat Notch1, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.

Gene Name Alternatives: Notch1 Motch

Poids moléculaire: >270 kDa, ~120 kDa and smaller fragments (due to proteolysis)

UniProt: Q01705

Pathways: Signalisation Notch, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development