DLG4 anticorps (PDZ Domain)

N° du produit ABIN1304920

Cet anticorps Souris Monoclonal détecte spécifiquement DLG4 dans WB, IHC, ICC, ELISA et IP. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 4+ publications.

Aperçu rapide pour DLG4 anticorps (PDZ Domain) (ABIN1304920)

Antigène: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DLG4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), ELISA, Immunoprecipitation (IP)

Classe de qualité: KO Validated

Clone: K28-43

Détail du produit anti-DLG4 anticorps

Épitope: AA 77-299, PDZ Domain

Fonction: Anti-PSD-95 Antibody

Specificité: No off-targets reported for recombinant Chapsyn-110, SAP97 or SAP102

Réactivité croisée: Poulet, Souris, Non-Human Primate, Rat

Attributs du produit: Our Anti-PSD 95 mouse monoclonal primary antibody is produced in-house from hybridoma clone K28/43. It is KO validated, detects chicken, human, mouse, non-human primate, and rat PSD 95, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Pureté: Purified mAbs are >90 % specific antibody.

Immunogène: Fusion protein amino acids 77-299 (PDZ domains 1 and 2) of human PSD-95 (accession number P78352) produced recombinantly in E. Coli

Isotype: IgG2a

Information d'application

Indications d'application:

Dilution Range: IP: 5 μg

Dilution Range: ICC: 1:500

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 24 months

Références pour anticorps anti-DLG4 (ABIN1304920)

Madore, Leyrolle, Morel, Rossitto, Greenhalgh, Delpech, Martinat, Bosch-Bouju, Bourel, Rani, Lacabanne, Thomazeau, Hopperton, Beccari, Sere, Aubert, De Smedt-Peyrusse, Lecours, Bisht, Fourgeaud et al.: "Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain. ..." dans: Nature communications, Vol. 11, Issue 1, pp. 6133, (2020) (PubMed).

Gonzalez-Lozano, Klemmer, Gebuis, Hassan, van Nierop, van Kesteren, Smit, Li: "Dynamics of the mouse brain cortical synaptic proteome during postnatal brain development." dans: Scientific reports, Vol. 6, pp. 35456, (2016) (PubMed).

Armstrong, Chung, Armstrong, Hochgeschwender, Jeong, Hawkes: "A novel somatostatin-immunoreactive mossy fiber pathway associated with HSP25-immunoreactive purkinje cell stripes in the mouse cerebellum." dans: The Journal of comparative neurology, Vol. 517, Issue 4, pp. 524-38, (2009) (PubMed).

Fischer, Foster, Scott, Sherwood: "Transient expression of LIM-domain transcription factors is coincident with delayed maturation of photoreceptors in the chicken retina." dans: The Journal of comparative neurology, Vol. 506, Issue 4, pp. 584-603, (2007) (PubMed).

Détails sur DLG4

Antigène: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Autre désignation: PSD 95

Sujet:

Synonyms: Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)

Description Logic: Our Anti-PSD 95 mouse monoclonal primary antibody is produced from hybridoma clone K28/43. It is KO validated, detects chicken, human, mouse, non-human primate, and rat PSD 95, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.

Gene Name Alternatives: DLG4 PSD95

Poids moléculaire: 95-110 kDa (varies with cell background due to phosphorylation)

UniProt: P78352

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity