COL3 anticorps

N° du produit ABIN135050

Il existe 29+ publications pour ce produit. L’anticorps anti-COL3 Polyclonal Chèvre est utilisé pour la détection de COL3 dans des échantillons de Humain, Rat, Souris, Lapin, Chien, Poulet, Boeuf (Vache), Chinchilla chinchilla, Cobaye, Hamster, Cheval, Porc, Macaque rhésus et Tree shrew. Il a été validé pour WB, ELISA, IHC (fro), ICC, IHC (p), FACS et IEM.

Aperçu rapide pour COL3 anticorps (ABIN135050)

Antigène: COL3 (Collagen, Type III (COL3))

Reactivité: Humain, Rat, Souris, Lapin, Chien, Poulet, Boeuf (Vache), Chinchilla chinchilla, Cobaye, Hamster, Cheval, Porc, Macaque rhésus, Tree shrew

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp COL3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunoelectron Microscopy (IEM)

Détail du produit anti-COL3 anticorps

Fonction: Goat Anti-Type III Collagen-UNLB

Specificité: Reacts with conformational determinants on type III collagen Referenced species reactivities include - Human 2,5,11,12,32,33,35-37 Chicken 22,23 Hamster 18,24 Mouse 4,6,13,15,34,39 Chinchilla 26 Porcine 1,5,17,29 Rat 5,10,14,20,31 Equine 25 Rabbit 9,16,19,21,38 Bovine 8,27 Feline 30 Rhesus 7 Canine 3,5 Guinea Pig 21 Tree Shrew 28

Réactivité croisée (Details): Exhibits < 10 % cross reactivity with collagen type II, III, IV, V and VI. The antibody has not been tested for reactivity with other ECM proteins (e.g., laminin, fibronectin).

Attributs du produit: Purified Anti-Type III Collagen antibody for use in ELISA, immunohistochemistry / immunocytochemistry, electron microscopy, flow cytometry, and western blotting assays.

Purification: Purified by affinity chromatography on type III collagen covalently linked to agarose, cross-adsorbed against Collagen types I, II, IV, V, and VI for minimal reactivity

Immunogène: Type III collagen

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Pooled antisera from goats hyperimmunized with type III collagen

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: Borate buffered saline, pH 8.2

Stock: 4 °C

Stockage commentaire: 2-8°C

Références pour anticorps anti-COL3 (ABIN135050)

Fernandes, Reilly, Schrock, Hocking, Oakes, Fowell: "CD4+ T Cell Interstitial Migration Controlled by Fibronectin in the Inflamed Skin." dans: Frontiers in immunology, Vol. 11, pp. 1501, (2020) (PubMed).

Sembach, Fink, Johansen, Boland, Secher, Thrane, Nielsen, Fosgerau, Vrang, Jelsing, Pedersen, Østergaard: "Impact of sex on diabetic nephropathy and the renal transcriptome in UNx db/db C57BLKS mice." dans: Physiological reports, Vol. 7, Issue 24, pp. e14333, (2020) (PubMed).

Becker, OConnell, Vo, Cain, Tampe, Bizarro, Sugimoto, McGow, Asara, Lovisa, McAndrews, Zielinski, Lorenzi, Zeisberg, Raza, LeBleu, Kalluri: "Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer." dans: Cell reports, Vol. 31, Issue 9, pp. 107701, (2020) (PubMed).

Buhl, Djudjaj, Klinkhammer, Ermert, Puelles, Lindenmeyer, Cohen, He, Borkham-Kamphorst, Weiskirchen, Denecke, Trairatphisan, Saez-Rodriguez, Huber, Olson, Floege, Boor: "Dysregulated mesenchymal PDGFR-β drives kidney fibrosis." dans: EMBO molecular medicine, Vol. 12, Issue 3, pp. e11021, (2020) (PubMed).

Dobie, Wilson-Kanamori, Henderson, Smith, Matchett, Portman, Wallenborg, Picelli, Zagorska, Pendem, Hudson, Wu, Budas, Breckenridge, Harrison, Mole, Wigmore, Ramachandran, Ponting, Teichmann, Marioni et al.: "Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis. ..." dans: Cell reports, Vol. 29, Issue 7, pp. 1832-1847.e8, (2020) (PubMed).

Welc, Flores, Wehling-Henricks, Ramos, Wang, Bertoni, Tidball: "Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy." dans: Nature communications, Vol. 10, Issue 1, pp. 2788, (2019) (PubMed).

Delestre-Delacour, Carmon, Laguerre, Estay-Ahumada, Courel, Elias, Jeandel, Rayo, Peinado, Sengmanivong, Gasman, Coudrier, Anouar, Montero-Hadjadje: "Myosin 1b and F-actin are involved in the control of secretory granule biogenesis." dans: Scientific reports, Vol. 7, Issue 1, pp. 5172, (2019) (PubMed).

He, Zhang, Tolosa, Goru, Chen, Misra, Robinson, Yuen: "A new, easily generated mouse model of diabetic kidney fibrosis." dans: Scientific reports, Vol. 9, Issue 1, pp. 12549, (2019) (PubMed).

Ellenbroek, de Haan, van Klarenbosch, Brans, van de Weg, Smeets, de Jong, Arslan, Timmers, Goumans, Hoefer, Doevendans, Pasterkamp, Meyaard, de Jager: "Leukocyte-Associated Immunoglobulin-like Receptor-1 is regulated in human myocardial infarction but its absence does not affect infarct size in mice." dans: Scientific reports, Vol. 7, Issue 1, pp. 18039, (2019) (PubMed).

Qiao, Dai, Nikolova, Jin, Li, Xiao, Li, Moy, Xiao: "Amelioration of Muscle and Nerve Pathology in LAMA2 Muscular Dystrophy by AAV9-Mini-Agrin." dans: Molecular therapy. Methods & clinical development, Vol. 9, pp. 47-56, (2018) (PubMed).

Wada, Kawada, Hirai, Toda, Iwamoto, Hasegawa, Sakai: "Enhanced anastomotic healing by Daikenchuto (TJ-100) in rats." dans: Scientific reports, Vol. 8, Issue 1, pp. 1091, (2018) (PubMed).

Westendorp, Büller, Karpus, van Dop, Koster, Versteeg, Koelink, Snel, Meisner, Roelofs, Uhmann, Ver Loren van Themaat, Heijmans, Hahn, Muncan, Wildenberg, van den Brink: "Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response." dans: Cellular and molecular gastroenterology and hepatology, Vol. 5, Issue 1, pp. 67-82.e1, (2018) (PubMed).

de Bruyn, Becker, Steenkamer, Wildenberg, Meijer, Buskens, Bemelman, Löwenberg, Ponsioen, van den Brink, DHaens: "Intestinal fibrosis is associated with lack of response to Infliximab therapy in Crohn's disease." dans: PLoS ONE, Vol. 13, Issue 1, pp. e0190999, (2018) (PubMed).

Pu, Zhang, Huang, Tian, He, Wang, Zhang, Liu, Li, Li, Zhao, Liu, Lu, Zhou, Huang, Nie, Yan, Hui, Lui, Zhou: "Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration." dans: Nature communications, Vol. 7, pp. 13369, (2018) (PubMed).

Poosti, Bansal, Yazdani, Prakash, Beljaars, van den Born, de Borst, van Goor, Hillebrands, Poelstra: "Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice." dans: Oncotarget, Vol. 7, Issue 34, pp. 54240-54252, (2018) (PubMed).

Hijmans, Shrestha, Sarpong, Yazdani, El Masri, de Jong, Navis, Vivès, van den Born: "High sodium diet converts renal proteoglycans into pro-inflammatory mediators in rats." dans: PLoS ONE, Vol. 12, Issue 6, pp. e0178940, (2017) (PubMed).

Hijmans, Rasmussen, Yazdani, Navis, van Goor, Karsdal, Genovese, van den Born: "Urinary collagen degradation products as early markers of progressive renal fibrosis." dans: Journal of translational medicine, Vol. 15, Issue 1, pp. 63, (2017) (PubMed).

Poosti, Pham, Oosterhuis, Poelstra, van Goor, Olinga, Hillebrands: "Precision-cut kidney slices (PCKS) to study development of renal fibrosis and efficacy of drug targeting ex vivo." dans: Disease models & mechanisms, Vol. 8, Issue 10, pp. 1227-36, (2016) (PubMed).

Yazdani, Hijmans, Poosti, Dam, Navis, van Goor, van den Born: "Targeting tubulointerstitial remodeling in proteinuric nephropathy in rats." dans: Disease models & mechanisms, Vol. 8, Issue 8, pp. 919-30, (2016) (PubMed).

Abdul, Dixon, Walker, Horabin, Smith, Weir, Brewster, Deehan, Mann, Borthwick: "Fibrosis is a common outcome following total knee arthroplasty." dans: Scientific reports, Vol. 5, pp. 16469, (2016) (PubMed).

Détails sur COL3

Antigène: COL3 (Collagen, Type III (COL3))

Autre désignation: TypeIII Collagen

Sujet:

Description: Goat Anti-Type III Collagen-UNLB

NCBI_Official_Symbol: COL3A1

Synoynms: COL3

ID gène: 1281

UniProt: P02461