COL3 anticorps (AA 1301-1400)

N° du produit ABIN669981

Détail du produit anti-COL3 anticorps

Antigène: COL3 (Collagen, Type III (COL3))

Épitope: AA 1301-1400

Reactivité: Humain, Rat, Souris, Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody is produced with an immunogen contained within the COLFI propeptide region, it will only recognize the full length Collagen III protein and not the mature form.

Réactivité croisée: Chien, Humain, Souris, Lapin, Rat

Homologie: Cow,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Collagen alpha 1(III) chain (C-terminal propeptide)

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-COL3 (ABIN669981)

Velázquez, Enos, Carson, Cranford, Bader, Sougiannis, Pritchett, Fan, Carson, Murphy: "miR155 deficiency aggravates high-fat diet-induced adipose tissue fibrosis in male mice." dans: Physiological reports, Vol. 5, Issue 18, (2018) (PubMed).

Bai, Wu, Hong, Zhang, Liu, Chen: "Anti‑fibrotic effect of Sedum sarmentosum Bunge extract in kidneys via the hedgehog signaling pathway." dans: Molecular medicine reports, Vol. 16, Issue 1, pp. 737-745, (2017) (PubMed).

Yu, Liu, Sun, Wang, Wang, Zhao, Dai, Zhao, Zhang, Li, Han, Lu, Dong, Liu, Yu, Li: "Chronic obstructive sleep apnea promotes aortic remodeling in canines through miR-145/Smad3 signaling pathway." dans: Oncotarget, Vol. 8, Issue 23, pp. 37705-37716, (2017) (PubMed).

Yang, Zhao, Wang, Liu, Ma, Huang, Liu: "Isolation and biological characterization of tendon-derived stem cells from fetal bovine." dans: In vitro cellular & developmental biology. Animal, Vol. 52, Issue 8, pp. 846-56, (2017) (PubMed).

Zhu, Hu, Yu, Ren, Hu: "High Molecular Weight Hyaluronic Acid Inhibits Fibrosis of Endometrium." dans: Medical science monitor : international medical journal of experimental and clinical research, Vol. 22, pp. 3438-3445, (2016) (PubMed).

Jiang, Chun, Wang, Du, Wang, Xiong: "Effect of transforming growth factor-β3 on the expression of Smad3 and Smad7 in tenocytes." dans: Molecular medicine reports, Vol. 13, Issue 4, pp. 3567-73, (2016) (PubMed).

Bai, Lu, Lin, Xu, Hu, Liang, Hong, Chen: "Sonic hedgehog-mediated epithelial-mesenchymal transition in renal tubulointerstitial fibrosis." dans: International journal of molecular medicine, Vol. 37, Issue 5, pp. 1317-27, (2016) (PubMed).

Su, Zhao, Shi, Zhang, Yu, Xie, Guo, Zhang, Liu, Shen, Wang, Li, Zhang, Zhou: "Let-7d suppresses growth, metastasis, and tumor macrophage infiltration in renal cell carcinoma by targeting COL3A1 and CCL7." dans: Molecular cancer, Vol. 13, pp. 206, (2016) (PubMed).

Wang, Li, Huang, Wang: "The influence of hypoxia during different pregnancy stages on cardiac collagen accumulation in the adult offspring." dans: BioMed research international, Vol. 2014, pp. 419805, (2015) (PubMed).

Zhao, Zhang, Chen, Gu, Ni, Shao, Wu, Qin: "Increased expression of NF-AT3 and NF-AT4 in the atria correlates with procollagen I carboxyl terminal peptide and TGF-β1 levels in serum of patients with atrial fibrillation." dans: BMC cardiovascular disorders, Vol. 14, pp. 167, (2015) (PubMed).

Détails sur COL3

Antigène: COL3 (Collagen, Type III (COL3))

Autre désignation: Collagen 3 (COL3 Produits)

Synonymes: anticorps PT, anticorps RPRGL2, anticorps THPH1, anticorps Cf-2, anticorps Cf2, anticorps FII, anticorps thrombin, anticorps prothrombin, anticorps coagulation factor II, thrombin, anticorps coagulation factor II, anticorps F2

Sujet:

Synonyms: EDS4A, Collagen alpha-1(III) chain, COL3A1

Background: Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.

ID gène: 1281

UniProt: P02461