CD32/CD16 anticorps

N° du produit ABIN135200

L’anticorps anti-CD32/CD16 Monoclonal Rat est utilisé pour la détection de CD32/CD16 dans des échantillons de Souris. Il a été validé pour FACS, IP, BR et IHC (fro).

Aperçu rapide pour CD32/CD16 anticorps (ABIN135200)

Antigène: CD32/CD16

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD32/CD16 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 93

Détail du produit anti-CD32/CD16 anticorps

Fonction: Rat Anti-Mouse CD16/32-LE/AF

Specificité: Mouse CD16/32

Attributs du produit: Low Endotoxin/Azide Free Anti-Mouse CD16/32 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, and blocking assays.

niveau d'endotoxine: Low Endotoxin

Immunogène: VH81X Tg B cells and T220 stromal cell line

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Agent conservateur: Azide free

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: 2-8°C

Détails sur CD32/CD16

Antigène: CD32/CD16

Autre désignation: CD16/32

Sujet: The lymphocyte Fc receptors recognize the Fc portion of IgG, presented either as immune complexes or as free antibody. The different classes of receptors are distinct because of varying size, tissue distribution and affinity for IgGs. The Fc type II receptor is expressed on a wide variety of cells including B cells, hematopoietic cells, monocyte/macrophages, neutrophils, platelets, Langerhans cells, eosinophils, basophils, trophoblasts, and endothelial cells of the placenta. The Fc type III receptors are higher affinity than the type II and are expressed on macrophages, NK cells and neutrophils. Both types of receptors can be expressed on the same cell and in varying ratios. The receptors are constitutively expressed, although cytokines and lymphokines can modulate their expression.4 Besides identifying FcR+ cells, monoclonal antibodies to the FcII/III receptor have been used to block Fc receptor binding of IgG, Fc-mediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on FcR for parasitic invasion.

ID gène: 14131

UniProt: P08508