CD40 Ligand anticorps

N° du produit ABIN135215

L’anticorps anti-CD40 Ligand Monoclonal produit chez le Hamster a été validé pour FACS. Il convient pour la détection de CD40 Ligand dans des échantillons provenant de Souris. }

Aperçu rapide pour CD40 Ligand anticorps (ABIN135215)

Antigène: CD40 Ligand (CD40LG)

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp CD40 Ligand est non-conjugé

Application: Flow Cytometry (FACS)

Clone: MR1

Détail du produit anti-CD40 Ligand anticorps

Specificité: Mouse CD154, Mr 39 kDa

Attributs du produit: Hamster Anti-Mouse CD154-UNLB

Purification: Purified

Immunogène: Activated mouse Th1 clone D1.6

Isotype: IgG

Information d'application

Indications d'application:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature , ELISA - Reported in literature
• Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Commentaires:

In vivo and in vitro blockage of CD154 function

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Agent conservateur: Without preservative

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C

Détails sur CD40 Ligand

Antigène: CD40 Ligand (CD40LG)

Autre désignation: CD154

Sujet: CD154, formerly known as CD40 ligand and gp39, is a type II integral membrane protein and a member of the tumor necrosis factor (TNF) family of ligands. It is an important accessory molecule in T cell-B cell costimulatory interactions, and is expressed predominantly on activated CD4+ T lymphocytes. It is also present on the surface of activated Th0, Th1, and Th2 T cell clones. Its expression is transient and cyclosporin-sensitive.

Pathways: Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints