Transferrin Receptor anticorps (FITC)

N° du produit ABIN135260

L’anticorps Rat Monoclonal anti-Transferrin Receptor a été validé pour FACS. Il convient pour détecter Transferrin Receptor dans des échantillons de Souris. Il y a 1 publication disponible.

Aperçu rapide pour Transferrin Receptor anticorps (FITC) (ABIN135260)

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin Receptor est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: RI7217

Détail du produit anti-Transferrin Receptor anticorps (FITC)

Specificité: Mouse CD71, Mr 95 kDa

Attributs du produit: Rat Anti-Mouse CD71-FITC

Purification: Ion exchange column

Immunogène: DMSO induced Friend erythroleukemia 745.6

Isotype: IgG2a

Information d'application

Indications d'application:

• Applications: FC - Quality tested , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature , Sep - Reported in literature , Drug Delivery - Reported in literature
• Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 0.5 mg in 1.0 mL of PBS/Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C

Références pour anticorps anti-Transferrin Receptor (FITC) (ABIN135260)

Balmus, Karp, Ng, Jackson, Adams, McIntyre: "A high-throughput in vivo micronucleus assay for genome instability screening in mice." dans: Nature protocols, Vol. 10, Issue 1, pp. 205-15, (2015) (PubMed).

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: CD71

Sujet: CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens, presumably reflecting the iron dependence of proliferation. Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin, the major iron-carrying protein. It may also be involved in signal transduction via its association with the T cell receptor chain.

Pathways: Transition Metal Ion Homeostasis