NK-1.1/CD161c anticorps

N° du produit ABIN135340

Cet anticorps Souris Monoclonal détecte spécifiquement NK-1.1/CD161c dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour NK-1.1/CD161c anticorps (ABIN135340)

Antigène: NK-1.1/CD161c (NK-1.1)

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NK-1.1/CD161c est non-conjugé

Application: Flow Cytometry (FACS)

Clone: PK136

Détail du produit anti-NK-1.1/CD161c anticorps

Specificité: Mouse NK1.1, Mr 39 kDa

Attributs du produit: Mouse Anti-Mouse NK1.1-UNLB

Purification: Purified

Immunogène: CE mouse spleen enriched for NK-1+ cells and bone marrow cells

Isotype: IgG2a

Information d'application

Indications d'application:

• Applications: FC - Quality tested , IHC - Reported in literature , IP - Reported in literature , Depletion - Reported in literature , CMCD - Reported in literature , Block - Reported in literature , Activ - Reported in literature
• Working Dilutions: Flow Cytometry FITC, BIOT, PACBLU, AF488, and AF700 conjugates 1 g/106 cells PE and APC conjugates 0.5 g/106 cells PE/CY7 and AF647 conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Commentaires:

Induction of proliferation of a subset of NK cells, In vivo depletion of NK1.1 cells, In vitro redirected lysis, In vitro cytotoxicity assays

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Agent conservateur: Without preservative

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C

Détails sur NK-1.1/CD161c

Antigène: NK-1.1/CD161c (NK-1.1)

Autre désignation: NK1.1

Sujet: NK1.1, a member of the NKR-P1 family of cell surface receptors, is a type II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells, as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57BL, NZB). NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells. This product does not react with NK cells of BALB/c mice.