CD8 alpha anticorps (PE)

N° du produit ABIN135479

L’anticorps Souris Monoclonal anti-CD8 alpha a été validé pour FACS. Il convient pour détecter CD8 alpha dans des échantillons de Porc. Il y a 2+ publications disponibles.

Aperçu rapide pour CD8 alpha anticorps (PE) (ABIN135479)

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reactivité: Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD8 alpha est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: 76-2-11

Détail du produit anti-CD8 alpha anticorps (PE)

Specificité: Porcine CD8α, Mr 35 kDa

Attributs du produit: Mouse Anti-Porcine CD8a-PE

Purification: Protein A

Immunogène: Fresh dd miniature swine thymocytes

Isotype: IgG2a

Information d'application

Indications d'application:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , IP - Reported in literature , Block - Reported in literature , Depletion - Reported in literature , CMCD - Reported in literature
• Working Dilutions: Flow Cytometry FITC, BIOT and AF488 conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Commentaires:

Cytotoxicity assays, In vivo depletion of CD8+ cells

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: 0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C

Références pour anticorps anti-CD8 alpha (PE) (ABIN135479)

Guo, Fu, Wang, Lu, Wei, Tang, Fan, Liu, Zhang, Zhang, Huang, Liu, Li, Wu, Liu: "A porcine circovirus type 2 (PCV2) mutant with 234 amino acids in capsid protein showed more virulence in vivo, compared with classical PCV2a/b strain." dans: PLoS ONE, Vol. 7, Issue 7, pp. e41463, (2012) (PubMed).

Fort, Fernandes, Nofrarias, Díaz, Sibila, Pujols, Mateu, Segalés: "Development of cell-mediated immunity to porcine circovirus type 2 (PCV2) in caesarean-derived, colostrum-deprived piglets." dans: Veterinary immunology and immunopathology, Vol. 129, Issue 1-2, pp. 101-7, (2009) (PubMed).

Détails sur CD8 alpha

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Autre désignation: CD8a

Sujet: Porcine CD8, a type I transmembrane glycoprotein, is expressed as either a CD8 homodimer or a CD8 heterodimer. It is found on most thymocytes, and on the suppressor/cytotoxic subpopulation of peripheral T cells. CD8 functions primarily as a co-receptor with MHC Class I-restricted T-cell receptors in antigen recognition.

Pathways: TCR Signaling