CD8 alpha anticorps (PE)

N° du produit ABIN135515

L’anticorps Souris Monoclonal anti-CD8 alpha a été validé pour FACS. Il convient pour détecter CD8 alpha dans des échantillons de Poulet. Il y a 4+ publications disponibles.

Aperçu rapide pour CD8 alpha anticorps (PE) (ABIN135515)

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reactivité: Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD8 alpha est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: CT-8

Détail du produit anti-CD8 alpha anticorps (PE)

Specificité: Chicken/Turkey/Guinea Fowl/Pigeon CD8α, Mr 34 kDa

Attributs du produit: Mouse Anti-Chicken CD8a-PE

Purification: Ion exchange column

Immunogène: Chicken thymocytes and Ig-negative blood leukocytes

Isotype: IgG1

Information d'application

Indications d'application:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Block - Reported in literature
• Working Dilutions: Flow Cytometry FITC, BIOT, AF488, and PACBLU conjugates 1 g/106 cells PE and CY5 conjugates 0.2 g/106 cells APC, SPRD, AF647, and AF700 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: 0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C

Références pour anticorps anti-CD8 alpha (PE) (ABIN135515)

Han, Renu, Patil, Schrock, Feliciano-Ruiz, Selvaraj, Renukaradhya: "Immune Response to Salmonella Enteritidis Infection in Broilers Immunized Orally With Chitosan-Based Salmonella Subunit Nanoparticle Vaccine." dans: Frontiers in immunology, Vol. 11, pp. 935, (2020) (PubMed).

Peng, Yu, Liang, Chi, Li, Jiang, Fang, Cui, Lai, Zhou, Zhou: "The mitochondrial and death receptor pathways involved in the thymocytes apoptosis induced by aflatoxin B1." dans: Oncotarget, Vol. 7, Issue 11, pp. 12222-34, (2017) (PubMed).

Peng, Zhang, Bai, Ding, Zeng, Yang, Fang, Chen: "Histological lesions, cell cycle arrest, apoptosis and T cell subsets changes of spleen in chicken fed aflatoxin-contaminated corn." dans: International journal of environmental research and public health, Vol. 11, Issue 8, pp. 8567-80, (2015) (PubMed).

Chen, Peng, Fang, Cui, Zuo, Deng, Chen, Geng, Lai, Tang, Yang: "Effects of dietary selenium on histopathological changes and T cells of spleen in broilers exposed to aflatoxin B1." dans: International journal of environmental research and public health, Vol. 11, Issue 2, pp. 1904-13, (2015) (PubMed).

Détails sur CD8 alpha

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Autre désignation: CD8a

Sujet: CD8 In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two chains, and (ii) a heterodimer of an chain and a chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8- and CD8-chains, a relatively large proportion of the CD8+ TCR- cells in the spleens of embryos and young chicks express only the -chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR- CD8 cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80 % of thymocytes, 15 % of blood mononuclear cells and 50 % of spleen cells, but < 1 % of cells in the bursa and bone marrow.

Pathways: TCR Signaling