Histone 3 anticorps (AA 26-30)
Aperçu rapide pour Histone 3 anticorps (AA 26-30) (ABIN1355846)
Antigène
Voir toutes Histone 3 (H3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 26-30
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Specificité
- The antibody detects endogenous level of total Histone H3 protein.
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Immunogène
- Peptide sequence around AA 26-30 (A-R-K-S-A) derived from Human Histone H3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Indications d'application
- Western blotting: 1:500-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C
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: "Paeoniflorin reduced BLP-induced inflammatory response by inhibiting the NF-?B signal transduction in pathway THP-1 cells." dans: Central-European journal of immunology / Polish Society for Immunology and eleven other Central-European immunological societies, Vol. 39, Issue 4, pp. 461-7, (2015) (PubMed).
: "Protective effects of Salvianolic acid B on Schwann cells apoptosis induced by high glucose." dans: Neurochemical research, Vol. 37, Issue 5, pp. 996-1010, (2012) (PubMed).
: "Inhibitory effects of salvianolic acid B on apoptosis of Schwann cells and its mechanism induced by intermittent high glucose." dans: Life sciences, Vol. 90, Issue 3-4, pp. 99-108, (2012) (PubMed).
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- Histone 3 (H3) (Histone H3 (H3))
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Autre désignation
- Histone H3
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Sujet
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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Poids moléculaire
- 17 kDa
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NCBI Accession
- NP_003520, NM_003529
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UniProt
- P68431
Antigène
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