MCAM anticorps (Biotin)
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- Antigène Voir toutes MCAM Anticorps
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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Reactivité
- Poulet
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MCAM est conjugé à/à la Biotin
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Application
- Flow Cytometry (FACS)
- Specificité
- Chicken/Turkey MCAM, Mr 98 kDa
- Attributs du produit
- Mouse Anti-Chicken MCAM-BIOT
- Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- Immunogène
- Mixture of E15 and E16 thymocytes from H.B15, H.B19, and H.B21 chicken embryos
- Clone
- C264
- Isotype
- IgG2b
- Top Product
- Discover our top product MCAM Anticorps primaire
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- Indications d'application
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- Applications: FC - Quality tested , ICC - Reported in literature , IP - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Volume d'échantillon
- 1 mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 0.5 mg in 1.0 mL of PBS/Sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
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Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C
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- Antigène
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
- Autre désignation
- MCAM (MCAM Produits)
- Synonymes
- anticorps CD146, anticorps MUC18, anticorps Muc18, anticorps 1-gicerin, anticorps AV025631, anticorps CD149, anticorps s-endo, anticorps s-gicerin, anticorps cd146, anticorps gicerin, anticorps id:ibd3512, anticorps mcam, anticorps MCAM, anticorps melanoma cell adhesion molecule, anticorps melanoma cell adhesion molecule b, anticorps MCAM, anticorps Mcam, anticorps mcamb
- Sujet
- Chicken MCAM, a member of the immunoglobulin superfamily of cell surface receptors, consists of the V-V-C2-C2-C2 Ig domains. It is a single chain glycoprotein with three mRNA splice variants. One has a short cytoplasmic tail, another has a long tail, and the third seems to lack transmembrane and cytoplasmic regions. It is highly homologous to gicerin, a molecule involved in neurite outgrowth and Wilm's kidney tumor progression in the chicken, and to the human melanoma progression molecule MUC18. Chicken MCAM is expressed by c-kit+ hematopoietic progenitor cells in embryonic bone marrow, thymocytes, and capillary endothelial cells. MCAM-expressing cells sorted from bone marrow are enriched in progenitors capable of differentiating into T cells when transferred into the appropriate thymic microenvironment. MCAM has been proposed to be involved in cellular adhesion and homing processes.
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