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Recombinant MCAM anticorps

MCAM Reactivité: Humain FACS, IHC, WB, IF, ELISA Hôte: Lapin Monoclonal 8A10 unconjugated Recombinant Antibody
N° du produit ABIN7127274
  • Antigène Voir toutes MCAM Anticorps
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 136
    • 54
    • 48
    • 15
    • 14
    • 9
    • 9
    • 8
    • 6
    • 2
    Humain
    Hôte
    • 95
    • 65
    • 8
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 87
    • 84
    Monoclonal
    Conjugué
    • 76
    • 15
    • 14
    • 11
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MCAM est non-conjugé
    Application
    • 93
    • 84
    • 67
    • 44
    • 23
    • 22
    • 18
    • 12
    • 12
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), ELISA
     Réactivité croisée
    Humain
    Purification
    Affinity-chromatography
    Immunogène
    A synthesized peptide
    Clone
    8A10
    Isotype
    IgG
    Top Product
    Discover our top product MCAM Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500, IF:1:30-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    Autre désignation
    MCAM (MCAM Produits)
    Synonymes
    anticorps CD146, anticorps MUC18, anticorps Muc18, anticorps 1-gicerin, anticorps AV025631, anticorps CD149, anticorps s-endo, anticorps s-gicerin, anticorps cd146, anticorps gicerin, anticorps id:ibd3512, anticorps mcam, anticorps MCAM, anticorps melanoma cell adhesion molecule, anticorps melanoma cell adhesion molecule b, anticorps MCAM, anticorps Mcam, anticorps mcamb
    Sujet

    Background: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

    Aliases: Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, Melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen, CD146, MCAM, MUC18

    UniProt
    P43121
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