LGR4 anticorps

N° du produit ABIN1381741

Cet anticorps Rat Monoclonal détecte spécifiquement LGR4 dans FACS et cELISA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour LGR4 anticorps (ABIN1381741)

Antigène: LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))

Reactivité: Humain, Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp LGR4 est non-conjugé

Application: Flow Cytometry (FACS), Cell-ELISA (cELISA)

Clone: BBX-3A8

Détail du produit anti-LGR4 anticorps

Specificité: Anti-human LGR4

Réactivité croisée: Souris

Attributs du produit: Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells

Purification: Protein G

Immunogène: genetic immunisation with cDNA encoding human LGR4

Isotype: IgG2a kappa

Information d'application

Indications d'application: Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Commentaires:

Synonyms: GPR48

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C

Stockage commentaire: short term: 2 °C - 8 °C, long term: -20 °C

Détails sur LGR4

Antigène: LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))

Autre désignation: LGR4

Sujet: LGR4 (Leucine-rich repeat- containing G protein-coupled receptor 4, GPR48) belongs to the superfamily of G protein-coupled receptors (GPCRs). It is a 951 amino acid multi-pass membrane protein and has multiple N-terminal leucine-rich repeats, which are important for interaction with the glycoprotein ligands, and 7 transmembrane domains. LGR4 is highly expressed in the adult human pancreas but also with moderate levels of expression in placenta, kidney, brain and heart. LGR4 functions as an orphan receptor that may be involved in physiologic activities throughout the cell. It is overexpressed in various cancer types and is thought to enhance carcinoma invasiveness and metastasis, suggesting an important role in tumor progression.

UniProt: Q9BXB1