UBE2L6 anticorps (AA 21-120)

N° du produit ABIN1385712

Cet anticorps anti-UBE2L6 est un anticorps Lapin Polyclonal détectant UBE2L6 dans ELISA, IHC (p), IF (cc), IF (p) et IHC (fro). Adapté pour Rat.

Aperçu rapide pour UBE2L6 anticorps (AA 21-120) (ABIN1385712)

Antigène: UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2L6 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-UBE2L6 anticorps

Épitope: AA 21-120

Réactivité croisée: Rat

Homologie: Human,Mouse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Ube2L6

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur UBE2L6

Antigène: UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Autre désignation: Ube2L6

Sujet:

Synonyms: Retinoic acid induced gene B protein, Retinoic acid-induced gene B protein, RIG B, RIG-B, UB2L6_HUMAN, UBCH 8, UBCH8, UBE2L6, Ubiquitin carrier protein, Ubiquitin carrier protein L6, Ubiquitin conjugating enzyme E2L 6, Ubiquitin protein ligase, Ubiquitin protein ligase L6, Ubiquitin-protein ligase L6, Ubiquitin/ISG15 conjugating enzyme E2 L6, Ubiquitin/ISG15-conjugating enzyme E2 L6.

Background: Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells, either free or covalently attached to cellular proteins. The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign, and improperly folded proteins by targeting them for proteosome degradation. Ubiquitin conjugating enzyme 8 (UBC8) is an E2 enzyme involved in the ubiquitin pathway for protein degradation. Like other E2 enzymes, UBC8 forms a thioester bond with ubiquitin in an E1-dependent manner. UBC8 binds to the human homolog of Drosophila ariadne (HHARI) and UBC7-associated protein (H7-AP1) as well as double ring-finger protein (Dorfin). UBC8 is enriched in the central nervous system and interacts with Parkin, a RING-finger-containing protein implicated in the pathogenesis of familial Parkinson?s disease. Parkin shares sequence homology with other UBC8 binding proteins such as HHARI and H7-AP1.

ID gène: 9246