MUL1 anticorps (AA 45-95)
Aperçu rapide pour MUL1 anticorps (AA 45-95) (ABIN1385942)
Antigène
Voir toutes MUL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 45-95
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human MUL1/RNF218
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
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Autre désignation
- MUL1
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Sujet
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Synonyms: E3 ubiquitin-protein ligase MUL1, C1orf166, E3 ubiquitin ligase, E3 ubiquitin protein ligase MUL1, GIDE, Growth inhibition and death E3 ligase, MAPL, Mitochondrial anchored protein ligase, Mitochondrial ubiquitin ligase activator of NFKB 1, MUL1, MULAN, Putative NF kappa B activating protein 266, RING finger protein 218, RNF218, RP23-25C1.10-002, MUL1_HUMAN.
Background: E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugatin.
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ID gène
- 79594
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UniProt
- Q969V5
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Pathways
- Positive Regulation of Endopeptidase Activity
Antigène
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