DUOX1 anticorps (AA 1-100)

N° du produit ABIN1386159

Cet anticorps anti-DUOX1 est un anticorps Lapin Polyclonal détectant DUOX1 dans ELISA, WB, IHC (p), ICC, IF (cc), IF (p) et IHC (fro). Adapté pour Humain, Souris et Rat. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour DUOX1 anticorps (AA 1-100) (ABIN1386159)

Antigène: DUOX1 (Dual Oxidase 1 (DUOX1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUOX1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DUOX1 anticorps

Épitope: AA 1-100

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DUOX1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-DUOX1 (ABIN1386159)

Wakatsuki, Furuno, Ohshima, Araki: "Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration." dans: The Journal of cell biology, Vol. 211, Issue 4, pp. 881-96, (2015) (PubMed).

Détails sur DUOX1

Antigène: DUOX1 (Dual Oxidase 1 (DUOX1))

Autre désignation: DUOX1

Sujet:

Synonyms: Dual oxidase 1, Dual oxidase 1 precursor, DUOX1, EC 1.11.1, EC 1.6.3.1, Flavoprotein NADPH oxidase, Large NOX 1, LNOX1, Long NOX 1, MGC138840, MGC138841, NADPH thyroid oxidase 1, Nicotinamide adenine dinucleotide phosphate oxidase, NOXEF1, THOX1, Thyroid oxidase 1, DUOX1_HUMAN.

Background: Dual oxidase 1 (DUOX1), a homolog of glycoprotein p91Phox, is expressed in airway epithelium and generates reactive oxygen species (ROS). DUOX1 is a multi-pass membrane protein predominantly expressed in thyrocytes and tracheal surface epithelial cells, as well as thyroid, trachea and bronchium. DUOX1 generates hydrogen peroxide, which is crucial for thyroid peroxidase and lactoperoxidase. It is also involved in thyroid hormone synthesis and lactoperoxidase-mediated antimicrobial defense in mucosa. DUOX1, which also plays a role in mucin expression, is widely expressed in fetal tissues.

ID gène: 53905