CDKL5 anticorps (AA 401-500)

N° du produit ABIN1386168

Cet anticorps anti-CDKL5 est un anticorps Lapin Polyclonal détectant CDKL5 dans WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) et ICC. Adapté pour Humain.

Aperçu rapide pour CDKL5 anticorps (AA 401-500) (ABIN1386168)

Antigène: CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDKL5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Détail du produit anti-CDKL5 anticorps

Épitope: AA 401-500

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CDKL5

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CDKL5

Antigène: CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))

Autre désignation: CDKL5

Sujet:

Synonyms: Cdkl5, CDKL5_HUMAN, Cyclin dependent kinase 5 transcript, Cyclin-dependent kinase-like 5, EIEE2, ISSX, Serine/threonine kinase 9, Serine/threonine-protein kinase 9, Stk9.

Background: Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin-dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. CDKL5 (cyclin-dependent kinase-like 5) is a 1030 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family. Expressed in brain, lung, kidney, prostate, ovary, placenta, pancreas and testis, CDKL5 is thought to play a role in cell cycle regulation. Defects in CDKL5 are a cause of several disorders, such as X-linked infantile spasm syndrome and Rett syndrome.

Pathways: Regulation of Cell Size