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RASSF5 anticorps (AA 321-418)

RASSF5 Reactivité: Humain IF (p), IF (cc), ELISA, IHC (fro), IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386228
  • Antigène Voir toutes RASSF5 Anticorps
    RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))
    Épitope
    • 14
    • 3
    • 2
    • 1
    • 1
    AA 321-418
    Reactivité
    • 25
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 20
    • 5
    Lapin
    Clonalité
    • 23
    • 2
    Polyclonal
    Conjugué
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RASSF5 est non-conjugé
    Application
    • 12
    • 12
    • 11
    • 6
    • 2
    • 2
    • 2
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Homologie
    Human,Mouse,Rat,Dog,Cow,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human RASSF5
    Isotype
    IgG
    Top Product
    Discover our top product RASSF5 Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Yang, Kong, Jin, Hergovich, Püschel: "Rassf5 and Ndr kinases regulate neuronal polarity through Par3 phosphorylation in a novel pathway." dans: Journal of cell science, Vol. 127, Issue Pt 16, pp. 3463-76, (2014) (PubMed).

  • Antigène
    RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))
    Autre désignation
    RASSF5 (RASSF5 Produits)
    Synonymes
    anticorps Maxp1, anticorps NORE1, anticorps NORE1A, anticorps NORE1B, anticorps RAPL, anticorps RASSF3, anticorps 1300019G20Rik, anticorps AU042887, anticorps Nore1, anticorps Nore1A, anticorps Nore1B, anticorps Rapl, anticorps Ras association domain family member 5, anticorps Ras association (RalGDS/AF-6) domain family member 5, anticorps RASSF5, anticorps Rassf5
    Sujet

    Synonyms: RAPL, Maxp1, NORE1, NORE1A, NORE1B, RASSF3, Ras association domain-containing protein 5, New ras effector 1, Regulator for cell adhesion and polarization enriched in lymphoid tissues, RASSF5

    Background: Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.

    ID gène
    83593
    UniProt
    Q8WWW0
    Pathways
    TCR Signaling
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