FAM84A anticorps (AA 151-250)

N° du produit ABIN1386304

Détail du produit anti-FAM84A anticorps

Antigène: FAM84A (Family with Sequence Similarity 84, Member A (FAM84A))

Épitope: AA 151-250

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM84A est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Pig,Chicken,Zebrafish

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NSE1/FAM84A

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-FAM84A (ABIN1386304)

Wang, Xu, Qin, Wang, Ma, Luo, Zhang: "Myocardin-related transcription factor-A is a key regulator in retinoic acid-induced neural-like differentiation of adult bone marrow-derived mesenchymal stem cells." dans: Gene, Vol. 523, Issue 2, pp. 178-86, (2013) (PubMed).

Détails sur FAM84A

Antigène: FAM84A (Family with Sequence Similarity 84, Member A (FAM84A))

Autre désignation: Nse1/Fam84a (FAM84A Produits)

Synonymes: anticorps 2310003N02Rik, anticorps 4731402F03Rik, anticorps AW125753, anticorps Nse1, anticorps NSE1, anticorps PP11517, anticorps RGD1305779, anticorps zgc:63724, anticorps family with sequence similarity 84, member A, anticorps family with sequence similarity 84 member A, anticorps Fam84a, anticorps FAM84A, anticorps fam84a

Sujet:

Synonyms: FAM 84A, Family with sequence similarity 84 member A, family with sequence similarity 84, member A, FLJ35392, Neurologic sensory protein 1, Neurological/sensory 1, NSE 1, NSE1, PP11517, Protein FAM84A, Protein NSE1.

Background: FAM84A is a 292 amino acid protein that belongs to the FAM84 family of proteins. Predominantly expressed in testis, FAM84A shares 44 % amino acid identity with the related protein FAM84B. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. Two FAM84A isoforms are expressed due to alternative splicing events. Isoform 2 can be phosphorylated on various serine residues and this phosphorylation is associated with cellular morphology. FAM84A is upregulated in colorectal cancer, lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells.

ID gène: 3859