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Transferrin Receptor anticorps (AA 621-720)

TFRC Reactivité: Humain, Souris FACS, WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386360
  • Antigène Voir toutes Transferrin Receptor (TFRC) Anticorps
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    Épitope
    • 15
    • 15
    • 10
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 621-720
    Reactivité
    • 195
    • 80
    • 28
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 111
    • 107
    • 31
    • 1
    • 1
    Lapin
    Clonalité
    • 156
    • 93
    • 1
    Polyclonal
    Conjugué
    • 110
    • 27
    • 20
    • 15
    • 10
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Transferrin Receptor est non-conjugé
    Application
    • 153
    • 138
    • 72
    • 67
    • 54
    • 41
    • 24
    • 21
    • 18
    • 12
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Dog,Cow,Pig,Horse,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Transferrin receptor
    Isotype
    IgG
    Top Product
    Discover our top product TFRC Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    Autre désignation
    Transferrin receptor (TFRC Produits)
    Synonymes
    anticorps Trfr, anticorps LOC100219280, anticorps tfr, anticorps cd71, anticorps tfr1, anticorps trfr, anticorps CD71, anticorps T9, anticorps TFR, anticorps TFR1, anticorps TR, anticorps TRFR, anticorps p90, anticorps 2610028K12Rik, anticorps AI195355, anticorps AI426448, anticorps AU015758, anticorps E430033M20Rik, anticorps Mtvr-1, anticorps Mtvr1, anticorps transferrin receptor, anticorps TFRC, anticorps Tfrc, anticorps tfrc
    Sujet

    Synonyms: T9, TR, TFR, p90, CD71, TFR1, TRFR, Transferrin receptor protein 1, TFRC

    Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

    ID gène
    7037
    UniProt
    P02786
    Pathways
    Transition Metal Ion Homeostasis
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