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ProSAPiP1 anticorps (AA 151-250)

PROSAPIP1 Reactivité: Souris, Rat WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386459
  • Antigène Tous les produits ProSAPiP1 (PROSAPIP1)
    ProSAPiP1 (PROSAPIP1) (ProSAP-Interacting Protein 1 (PROSAPIP1))
    Épitope
    • 15
    • 2
    • 2
    • 1
    AA 151-250
    Reactivité
    • 17
    • 17
    • 4
    Souris, Rat
    Hôte
    • 17
    • 2
    Lapin
    Clonalité
    • 19
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ProSAPiP1 est non-conjugé
    Application
    • 19
    • 13
    • 12
    • 12
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ProSAPiP1
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ProSAPiP1 (PROSAPIP1) (ProSAP-Interacting Protein 1 (PROSAPIP1))
    Autre désignation
    ProSAPiP1 (PROSAPIP1 Produits)
    Synonymes
    anticorps PROSAPIP1, anticorps RP5-1187M17.10, anticorps Prosapip1, anticorps leucine zipper tumor suppressor family member 3, anticorps leucine zipper, putative tumor suppressor family member 3, anticorps LZTS3, anticorps Lzts3
    Sujet

    Synonyms: PROSAPIP1, Leucine zipper putative tumor suppressor 3, ProSAP-interacting protein 1, LZTS3, KIAA0552

    Background: The ProSAP family of proteins contain many protein-protein interaction domains and serve as scaffolding mediators within the post-synaptic density (PSD) of excitatory brain synapses. The PSD is an electron-dense structure underneath the post-synaptic plasma membrane of excitatory synapses that anchors and clusters glutamate receptors opposite to the pre-synaptic neurotransmitter release site. Shank proteins contain PDZ modular domains that coordinate the synaptic localization of ion channels, receptors, signaling enzymes, and cell adhesion molecules. The PDZ domain mediates protein-protein interactions via the recognition of a conserved sequence motif at the C-terminus of their target protein(s). ProSAPiP1 (proline rich synapse associated protein interacting protein 1) is a 673 amino acid protein that interacts with the PDZ domain of Shank 3. ProSAPiP1 expression is brain-specific with highest expression within the cerebellum, hippocampus and cerebral cortex.

    ID gène
    9762
    UniProt
    O60299
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