ProSAPiP1 anticorps (C-Term)
Aperçu rapide pour ProSAPiP1 anticorps (C-Term) (ABIN6991188)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 590-640, C-Term
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Purification
- Prosapip1 Antibody is affinity chromatography purified via peptide column.
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Immunogène
- Prosapip1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human Prosapip1. The immunogen is located within amino acids 590 - 640 of Prosapip1.
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Isotype
- IgG
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Indications d'application
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Prosapip1 antibody can be used for detection of Prosapip1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Prosapip1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- Prosapip1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ProSAPiP1 (PROSAPIP1) (ProSAP-Interacting Protein 1 (PROSAPIP1))
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Autre désignation
- Prosapip1
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Sujet
- Prosapip1 Antibody: Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3's PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed 'Fezzins'. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.
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ID gène
- 9762
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NCBI Accession
- NP_055546
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UniProt
- O60299
Antigène
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